What Are the Clinical Symptoms of Lupus Nephritis

The clinical manifestations of lupus nephritis is the external manifestation of renal fibrosis. Its essence is the inherent destruction of the kidney cells, extracellular matrix caused by the proliferation of proliferation, with the kidney cells are gradually replaced by extracellular matrix, lupus nephritis clinical manifestations of the more serious symptoms. About 11 diagnostic criteria, if someone's load among the 4 or 4 or more, out of infection, cancer and other connective tissue lesions, how can the systemic lupus erythematosus; and at the same time with seven kidneys Lesions can be diagnosed with lupus nephritis.

1, cheek erythema flat or high from the two zygomatic prominence of bleeding fixed erythema.

2, discoid erythema tablets higher than the skin erythema, adhesion of keratinectomy and hair follicle suppository; old lesions can occur atrophic scar.

3, light allergy on the sun has a clear reaction, causing rash, can be known from the case or by the doctor observed.

4, oral ulcers can be observed oral or nasopharyngeal ulcers, usually painless.

5, arthritis non-invasive arthritis, involving two or more peripheral joints, tenderness, swelling or effusion.

6, serositis pleurisy or pericarditis

7, kidney disease urine protein greater than or equal to 0.5g / 24h (or greater than +++), or tube (red blood cells, hemoglobin, granular tube or mixed tube type).

8, neuropathy seizures or psychosis, due to drugs or known metabolic disorders caused by the exception.

9, hematological disorders hemolytic anemia or leukopenia, or lymphopenia, or thrombocytopenia.

10, immunological abnormal anti-dsDNA antibody was positive, or anti-Sm antibody was positive, or anti-phospholipid antibody positive (including anticardiolipin antibodies, or lupus anticoagulant, or at least 6 months of syphilis serum false positive, three With a positive).

11, anti-nuclear antibodies: at any time and unused drugs induced "drug-induced lupus" in the case of anti-nuclear antibodies showed abnormal.